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  • In vitro Metabolism
  • In vivo DMPK
  • Drug Interactions
  • Quantitative Bioanalysis
  • Permeability and Transporters
  • Physicochemistry and Binding
  • In vitro Toxicology
  • Biologics
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  2. Quantitative Bioanalysis chevron_right
  3. Bioanalysis, several tissues
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Bioanalysis, several tissues

Samples delivered by the Sponsor will be analyzed using a UPLC/MS/MS method developed for the purpose to determine tissue concentration levels of the test compound.
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Tissue concentrations

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Excel report
(full report available per request)

Background

We offer quantitative bioanalytical services (non-GLP) for all drug modalities, e.g., small molecules, peptides, oligonucleotides, antibodies and ADCs, either as a part of complete in vivo DMPK packages, or after the delivery of samples by our globally distributed customers. Our import permit covers a wide range of species, but, if a case-specific permit is required (CITES), we’ll apply that from the local authority, and the applications are typically processed quickly. We are also happy to support our customers in organizing the shipments when needed. Modern state-of-the-art equipment including LC/MS/MS and LC/HR-MS systems are used for the studies and chosen depending on the nature and need for each study. Due to the large variety of chemistries of test compounds and the complexity of certain biological matrices, our analytical tool kit is broad and comprises the majority of chromatographic options currently available (reverse phase, HILIC, chiral), and sample preparations range from simple precipitation to complex solid phase extraction combined with chemical derivatization. Analysis of radiolabeled compounds with UPLC-online-radio detection is also available.

Bioanalysis, several tissues is backordered and will ship as soon as it is back in stock.

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Admescope

Admescope is a preclinical contract research organization (CRO) providing tailor-made ADME-Tox (Absorption, Distribution, Metabolism, Excretion and Toxicity) services for drug discovery and development companies.

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